"Sin is the monarch that rules the heart of every man. It is the first lord of the
Sin is the moral and spiritual disease for which man has no cure. "Can the Ethiopian change his skin or the leopard his spots? Then you also can do good who are accustomed to do evil" (Jer. 13:23)
Sin dominates the mind. Romans 1:21 indicates that men have a reprobate mind given over to evil and lust.
Sin dominates the will. According to Jeremiah 44:15-17, men desire to do evil because their will is controlled by sin.
Sin dominates the emotions and the affections. The natural man does not want his sin cured because he loves darkness rather than light (John 3:19).
Sin brings men under the control of Satan. Ephesians 2:2 teaches that men are guided by "the prince of the power of the air, of the spirit that is now working in the sons of disobedience."
Sin brings people under divine wrath. According to Ephesians 2:3, unsaved people are "children of wrath."
Sin subjects men to misery. Job said, "Man is born for trouble, as sparks fly upward" (Job 5:7)." There is no peace for the wicked, says the Lord (Isa. 48:22)
Excerpt from "Alone with God" by J. MacArthur